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Abbott achieved positive results from a Phase II dose-ranging study of atrasentan, a highly selective endothelin A receptor antagonist in development to help slow chronic kidney disease (CKD) progression in patients with type 2 diabetic kidney disease.
November 23, 2010
By: Tim Wright
Editor-in-Chief, Contract Pharma
Abbott achieved positive results from a Phase II dose-ranging study of atrasentan, a highly selective endothelin A receptor antagonist in development to help slow chronic kidney disease (CKD) progression in patients with type 2 diabetic kidney disease. Results suggest that atrasentan, used with renin-angiotensin system (RAS) inhibitors, may reduce the presence of protein in urine for patients with type 2 diabetes. Albuminuria is the main sign of diabetic nephropathy and as kidney function decrea...
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